Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831619 | 0.85 | ADA (0.42) | ADABCHEHTR3ATARBP2MAOA | |
| SCHEMBL4583166 | 0.82 | ADA (0.51) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL6831661 | 0.78 | ADA (0.42) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL4583221 | 0.73 | ADA (0.46) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL6830817 | 0.72 | ADA (0.41) | ADABCHEHTR3ATARBP2MAOA | |
| SCHEMBL4585646 | 0.72 | ADA (0.37) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL4585651 | 0.72 | ADA (0.37) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL4582949 | 0.71 | HTR3A (0.39) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL4582942 | 0.71 | HTR3A (0.39) | ADABCHEMTNR1AMTNR1BHTR3A | |
| SCHEMBL4582944 | 0.71 | HTR3A (0.39) | ADABCHEMTNR1AMTNR1BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474421-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068768-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | disclosed |