Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288913 | 0.85 | ALDH1A1 (0.56) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL11039202 | 0.84 | ALDH1A1 (0.62) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL27770727 | 0.82 | KMT2A (0.60) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL4688815 | 0.82 | KMT2A (0.60) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL790857 | 0.82 | KMT2A (0.60) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL31337846 | 0.81 | ALDH1A1 (0.59) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL6129940 | 0.81 | KMT2A (0.58) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL6983963 | 0.81 | KMT2A (0.58) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL15256939 | 0.81 | ALDH1A1 (0.59) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL859237 | 0.81 | NPC1 (0.61) | KMT2ATSHRMEN1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260090547-A1 | BIO-INSECTICIDES FROM WASTE BIOMASS | UNIVERSITY OF DELAWARE (US) | 2026-04-02 | — | — | US | disclosed |
| CN-106588644-B | A kind of synthetic method of carboxylic acid ester compound | 杭州师范大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-108349920-A | OXIDATION CHEMISTRY ON FURAN ALDEHYDES | 微麦德斯公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-106588644-A | Synthesis method of carboxylic ester compound | 杭州师范大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-101646427-B | Inhibitors of akt activity | SMITHKLINE BEECHAM CORP US | 2013-06-12 | — | — | CN | disclosed |
| EP-1402895-A1 | Benzimidazole inhibitors of fructose 1,6-biphosphatase | Metabasis Therapeutics, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0970095-B1 | NOVEL BENZIMIDAZOLE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | METABASIS THERAPEUTICS INC (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6399782-B1 | ANTIDIABETIC AGENTS | METABASIS THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| US-6110903-A | INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE AT THE AMP SITE; ADMINISTERING TO TREAT DIABETES AND INHIBIT GLUCONEOGENESIS; 5-FLUORO-7-BROMO-1-ISOBUTYL-2-(2-PHOSPHONO-5-FURANYL) BENZIMIDAZOLE, FOR EXAMPLE | SANKYO COMPANY LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0970095-A1 | NOVEL BENZIMIDAZOLE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | Metabasis Therapeutics, Inc. (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039343-A9 | NOVEL BENZIMIDAZOLE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | — | 1999-01-21 | — | — | WO | disclosed |
| WO-1998039343-A1 | NOVEL BENZIMIDAZOLE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | METABASIS THERAPEUTICS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260090547-A1 | BIO-INSECTICIDES FROM WASTE BIOMASS | PTMS, DDT, BCHE | KMT2A 1449/4885TSHR 365/4885MEN1 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.