SCHEMBL790857

SCHEMBL790857

O=C(OCO)c1ccco1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
HTT P42858 1/20 0.59
ALDH1A1 P00352 6/20 0.55
TSHR P16473 2/20 0.55
MEN1 O00255 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
LMNA P02545 2/20 0.53
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.51
KDM4E B2RXH2 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GLA P06280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039202 0.86 ALDH1A1 (0.62) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL4661575 0.85 ALDH1A1 (0.57) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL4688815 0.84 KMT2A (0.60) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL27770727 0.84 KMT2A (0.60) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL6129940 0.82 KMT2A (0.58) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL31337846 0.82 ALDH1A1 (0.59) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL6830855 0.82 KMT2A (0.58) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL6983963 0.82 KMT2A (0.58) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL15256939 0.82 ALDH1A1 (0.59) KMT2AHTTALDH1A1TSHRMEN1
SCHEMBL859237 0.82 NPC1 (0.61) KMT2AHTTALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3400090-B1 CATALYST COMPOSITIONS AND AMMOXIDATION PROCESSES ASCEND PERFORMANCE MAT OPERATIONS LLC (US) 2020-11-18 EP claimed
EP-2233476-B1 Preparation of an ether of 2,5-(hydroxymethyl)furfural (HMF) from a fructose source, an alcohol solvent and an acid catalyst ARCHER DANIELS MIDLAND CO (US) 2013-08-28 EP claimed
CN-101809010-B Hydroxymethylfurfural ethers from sugars or HMF and mixed alcohols FURANIX TECHNOLOGIES BV 2013-01-16 CN claimed
CN-101809010-A hydroxymethylfurfural ethers from sugars or hmf and mixed alcohols FURANIX TECHNOLOGIES BV 2010-08-18 CN claimed
CN-101400666-A Synthesis method and application of 5-alkoxymethylfurfural ether AVANTIUM INT BV (NL) 2009-04-01 CN claimed
CN-119013263-A Cooling process for producing ACFC with purified increased crystal size 伊士曼化工公司 2024-11-22 CN disclosed
EP-3810584-A1 AN OXIDATION PROCESS TO PRODUCE 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS(ACFC) Eastman Chemical Company (US) 2021-04-28 EP disclosed
CN-110191923-A Bituminous composition comprising the humin obtained from the dehydration of carbohydrate 阿凡田知识中心有限公司 2019-08-30 CN disclosed
CN-105801528-B With metal catalyst reduction HMF ether 阿彻丹尼尔斯米德兰德公司 2019-06-21 CN disclosed
US-10316011-B2 Process for the production of 2, 5-furandicarboxylic acid (FDCA) ANNIKKI GMBH (AT) 2019-06-11 US disclosed
CN-109867642-A A kind of method that boehmite efficient catalytic cellulose prepares 5 hydroxymethyl furfural 盐城工学院 2019-06-11 CN disclosed
US-20180362486-A1 PROCESS FOR THE PRODUCTION OF 2, 5-FURANDICARBOXYLIC ACID (FDCA) Novolana GmbH (AT) 2018-12-20 US disclosed
US-20120196335-A1 LIGF-TYPE TRANSFORMANTS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS ALIGNA TECHNOLOGIES, INC. 2012-08-02 US disclosed
CN-101400666-B Synthesis method and application of 5-alkoxymethylfurfural ether AVANTIUM INT BV 2012-07-11 CN disclosed
WO-2012036884-A2 BIOPRODUCTION OF AROMATIC CHEMICALS FROM LIGNIN-DERIVED COMPOUNDS ALIGNA TECHNOLOGIES, INC. (US) 2012-03-22 WO disclosed
CN-102161918-A Use of 5-alkoxymethylfurfural ethers FURANIX TECHNOLOGIES BV 2011-08-24 CN disclosed
CN-101809010-A hydroxymethylfurfural ethers from sugars or hmf and mixed alcohols FURANIX TECHNOLOGIES BV 2010-08-18 CN disclosed
EP-2033958-A1 Hydroxymethylfurfural ethers from sugars and di- and triols Furanix Technologies B.V (NL) 2009-03-11 EP disclosed
EP-1292585-A1 BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS Takeda Chemical Industries, Ltd. (JP) 2003-03-19 EP disclosed
WO-2001098282-A1 BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 2001-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180362486-A1 PROCESS FOR THE PRODUCTION OF 2, 5-FURANDICARBOXYLIC ACID (FDCA) HPD, FDPS, FDFT1 KMT2A 1330/4885HTT 1532/4885ALDH1A1 204/4885
US-10316011-B2 Process for the production of 2, 5-furandicarboxylic acid (FDCA) HPD, FDPS, FDFT1 KMT2A 1330/4885HTT 1532/4885ALDH1A1 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.