Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825969 | 0.77 | SCN10A (0.52) | SCN10AKMT2AKIF18ATRPV1ALDH1A1 | |
| SCHEMBL6830991 | 0.74 | SCN10A (0.48) | SCN10AKMT2AKIF18ATRPV1ALDH1A1 | |
| SCHEMBL6643128 | 0.72 | ALDH1A1 (0.53) | SCN10AKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6646172 | 0.72 | KMT2A (0.63) | KMT2ATRPV1ALDH1A1TSHRMAPT | |
| SCHEMBL6825968 | 0.71 | SCN10A (0.41) | SCN10AKMT2AKIF18ATRPV1ALDH1A1 | |
| SCHEMBL6646082 | 0.71 | SCN10A (0.46) | SCN10ATRPV1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6826031 | 0.70 | SCN10A (0.47) | SCN10AKMT2ATRPV1ALDH1A1MAPT | |
| SCHEMBL6645120 | 0.69 | ALDH1A1 (0.53) | SCN10AKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6647449 | 0.69 | PDE7A (0.47) | SCN10ATRPV1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6829355 | 0.68 | SCN10A (0.39) | SCN10AKMT2AKIF18ATRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |