Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829403 | 0.89 | SCN10A (0.63) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6830991 | 0.86 | SCN10A (0.48) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6828987 | 0.86 | SCN10A (0.52) | SCN10AALDH1A1KDM4EKIF18A | |
| SCHEMBL6826031 | 0.82 | SCN10A (0.47) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6643128 | 0.82 | ALDH1A1 (0.53) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6829454 | 0.82 | KMT2A (0.64) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6645120 | 0.82 | ALDH1A1 (0.53) | SCN10AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6828922 | 0.81 | SCN10A (0.48) | SCN10AALDH1A1MAPTGAAKDM4E | |
| SCHEMBL6646172 | 0.78 | KMT2A (0.63) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL6645230 | 0.78 | SMN1; SMN2 (0.44) | SCN10AALDH1A1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |