Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819944 | 0.82 | TDP1 (0.64) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL10350330 | 0.81 | ALDH1A1 (0.66) | CES1CA1CA2TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10548858 | 0.81 | TDP1 (0.62) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL7540166 | 0.81 | TSHR (0.66) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL1813256 | 0.79 | CES1 (0.68) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL1398000 | 0.77 | CES1 (0.64) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL10940236 | 0.77 | CES1 (0.64) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL4908654 | 0.77 | MAPK1 (0.55) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL762542 | 0.77 | CES1 (0.77) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL28337082 | 0.77 | CES1 (0.77) | CES1CA1CA2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743585-B2 | COMPLEXING IN SOLVENT | AGILENT TECHNOLOGIES, INC. | 2004-06-01 | — | — | US | disclosed |
| US-20020025539-A1 | Methods for preparing conjugates | DELLINGER DOUGLAS J (US) | 2002-02-28 | — | — | US | disclosed |