Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.64 |
| ▸ | KDR | P35968 | 15/20 | 0.64 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | KIF5B | P33176 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826353 | 0.86 | SRC (0.60) | SRCKDREGFR | |
| SCHEMBL6829839 | 0.84 | SRC (0.60) | SRCKDREGFRRETKIF5B | |
| SCHEMBL6830881 | 0.84 | SRC (0.77) | SRCKDREGFR | |
| SCHEMBL6832867 | 0.84 | SRC (0.79) | SRCKDREGFR | |
| SCHEMBL6830967 | 0.82 | SRC (0.67) | SRCKDREGFR | |
| SCHEMBL6823586 | 0.82 | SRC (0.61) | SRCKDREGFRRETKIF5B | |
| SCHEMBL3280052 | 0.82 | SRC (0.67) | SRCKDREGFRRETKIF5B | |
| SCHEMBL6823799 | 0.79 | EGFR (0.52) | SRCKDREGFRRETKIF5B | |
| Trifluoroacetic Acid SCHEMBL6829065 | 0.77 | SRC (0.57) | SRCKDREGFR | |
| SCHEMBL6819634 | 0.76 | SRC (0.61) | SRCKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004081000-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |