Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.86 |
| ▸ | CES2 | O00748 | 3/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454122 | 1.00 | CES1 (0.86) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL31374765 | 0.93 | CES1 (1.00) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL2156825 | 0.93 | CES1 (1.00) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL11295400 | 0.91 | CES2 (0.89) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL31454134 | 0.91 | CES2 (0.89) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL9126277 | 0.88 | CES1 (0.77) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL11321858 | 0.88 | CES1 (0.77) | CES1CES2TP53TSHRALDH1A1 | |
| Benzil SCHEMBL27905655 | 0.87 | CES2 (0.81) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL3234327 | 0.86 | CES2 (0.68) | CES1CES2TP53TSHRALDH1A1 | |
| SCHEMBL1370034 | 0.85 | CES1 (1.00) | CES1CES2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077701-A1 | Estrogen receptor modulators | CHIRON CORPORATION (US) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077701-A1 | Estrogen receptor modulators | ESR1, ESR2, GPER1 | CES1 801/4885CES2 3073/4885TP53 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.