SCHEMBL6832097

SCHEMBL6832097

Cc1ccccc1C(=O)N(C)N

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
TSHR P16473 2/20 0.49
MAPK1 P28482 1/20 0.49
HPGD P15428 2/20 0.44
MYC P01106 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
HTT P42858 1/20 0.42
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11560303 0.98 KMT2A (0.54) KMT2ATSHRMAPK1HPGDMYC
SCHEMBL30037151 0.83 KMT2A (0.59) KMT2ATSHRMAPK1HPGDERCC5
SCHEMBL11216342 0.83 KMT2A (0.59) KMT2ATSHRMAPK1HPGDMYC
SCHEMBL354228 0.83 KMT2A (0.59) KMT2ATSHRMAPK1HPGDERCC5
SCHEMBL11318283 0.82 KMT2A (0.50) KMT2ATSHRMAPK1HPGDMYC
Hydrochloric Acid SCHEMBL1776796 0.81 KMT2A (0.58) KMT2ATSHRMAPK1HPGDERCC5
SCHEMBL3634403 0.81 KMT2A (0.58) KMT2ATSHRMAPK1HPGDERCC5
SCHEMBL15086632 0.80 KMT2A (0.45) KMT2ATSHRMAPK1HPGDMYC
SCHEMBL11673653 0.80 KMT2A (0.53) KMT2ATSHRMAPK1HPGDMYC
SCHEMBL9254635 0.79 KDM4E (0.53) KMT2ATSHRHPGDMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097386-A1 SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS EUROFARMA LABORATÓRIOS S.A (BR) 2023-06-08 WO disclosed
US-20040106724-A1 Natural rubber produced from latex and composition comprising the same BRIDGESTONE CORPORATION (JP) 2004-06-03 US disclosed
EP-1332161-A2 DRYING PROCESSES FOR NATURAL RUBBER, STABILIZED NR COMPOSITIONS Bridgestone Corporation (JP) 2003-08-06 EP disclosed
WO-2002038667-A2 NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME BRIDGESTONE CORPORATION (JP) 2002-05-16 WO disclosed
US-4151169-A DECYCLIZATION, CYCLIZATION GRUPPO LEPETIT (IT) 1979-04-24 US disclosed
US-4119635-A SEDATIVES, HYPNOTICS, TRANQUILIZERS GRUPPO LEPETIT S.P.A. (IT) 1978-10-10 US disclosed