Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30598338 | 0.85 | SMN1; SMN2 (0.55) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL538290 | 0.85 | SMN1; SMN2 (0.55) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL29287849 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| Hydrochloric Acid SCHEMBL15569994 | 0.83 | SMN1; SMN2 (0.53) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL10609398 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL28814836 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL27938205 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL6832097 | 0.79 | KMT2A (0.56) | ALDH1A1MAPTGAAHPGDTSHR | |
| SCHEMBL23891117 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL3628079 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10CFTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441948-A | Treatment of angina pectoris | EGIS GYOGYSZERGYAR RT. (HU) | 1995-08-15 | — | — | US | disclosed |