Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210384 | 1.00 | P2RY14 (0.44) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL442715 | 0.93 | P2RY14 (0.48) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL8538694 | 0.89 | P2RY14 (0.44) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL8970268 | 0.88 | P2RY14 (0.46) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL9157699 | 0.84 | SLC28A1 (0.53) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL442714 | 0.81 | SLC28A1 (0.43) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL2114483 | 0.81 | DUT (0.52) | P2RY14P2RY6P2RY2SLC28A1SLC28A2 | |
| SCHEMBL20603109 | 0.80 | P2RY14 (0.38) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL8210400 | 0.80 | P2RY6 (0.54) | P2RY14P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL8209464 | 0.80 | P2RY6 (0.54) | P2RY14P2RY6P2RY2P2RY4SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747142-B1 | FOR HIGHLY FUNCTIONALIZED OLIGONUCLEOTIDES OR NUCLEOSIDES; INCORPORATING MULTIPLE PRECURSOR GROUPS INTO ONE NUCLEOTIDE | FIDELITY SYSTEMS, INC. | 2004-06-08 | — | — | US | disclosed |
| US-6090932-A | Method of preparation of known and novel 2'-modified nucleosides by intramolecular nucleophilic displacement | PROLIGO LLC (US) | 2000-07-18 | — | — | US | disclosed |