Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | DUT | P33316 | 2/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442715 | 0.91 | P2RY14 (0.48) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL442714 | 0.88 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL27741782 | 0.84 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL7524816 | 0.84 | SLC28A1 (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8970268 | 0.84 | P2RY14 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8538694 | 0.84 | P2RY14 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL6832098 | 0.84 | P2RY14 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL8210384 | 0.84 | P2RY14 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL154356 | 0.83 | SLC28A1 (0.60) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL29891224 | 0.83 | SLC28A1 (0.38) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378706-B1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-12-28 | — | — | EP | claimed |
| US-5470967-A | Hybridization probes to detect nucleic acid sequences | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0517796-B1 | OLIGONUCLEOTIDE ANALOGS | DU PONT MERCK PHARMA (US) | 1995-04-19 | — | — | EP | disclosed |