SCHEMBL6832141

SCHEMBL6832141

CCCC(C)(CC(=O)OCC)SCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.44
HSD11B1 P28845 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MMP8 P22894 1/20 0.40
TSHR P16473 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
PRMT1 Q99873 1/20 0.39
ALDH1A1 P00352 3/20 0.38
POLB P06746 2/20 0.38
CYP2C9 P11712 1/20 0.38
METAP2 P50579 1/20 0.37
RECQL P46063 1/20 0.37
ALOX5 P09917 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PRNP P04156 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6832085 0.75 CYP3A4 (0.46) TSHRCYP1A2CYP3A4CYP2D6PRMT1
SCHEMBL9712251 0.74 MMP8 (0.52) PPIDNPC1RAB9ASMN1; SMN2MMP8
SCHEMBL4074798 0.72 PPID (0.46) PPIDHSD11B1SMN1; SMN2ALOX5
SCHEMBL11771628 0.71 MMP8 (0.50) PPIDNPC1RAB9ASMN1; SMN2MMP8
SCHEMBL3256326 0.71 NPC1 (0.62) PPIDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL7764897 0.71 PPID (0.42) PPIDHSD11B1NPC1RAB9ASMN1; SMN2
SCHEMBL7764894 0.71 PPID (0.42) PPIDHSD11B1NPC1RAB9ASMN1; SMN2
SCHEMBL9037437 0.71 MMP8 (0.52) PPIDHSD11B1SMN1; SMN2MMP8CYP3A4
SCHEMBL5972695 0.71 SMN1; SMN2 (0.47) PPIDHSD11B1RAB9ASMN1; SMN2TSHR
SCHEMBL5750562 0.70 MMP8 (0.51) PPIDSMN1; SMN2MMP8ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6805893-B2 3-MERCAPTO-2-METHYL-BUTAN-1-OL STEREOISOMERS OR ENANTIOMORPHS ARE USED TO FLAVOR FOODS AND/OR BEVERAGES GIVAUDAN SA (CH) 2004-10-19 US disclosed
US-20040047960-A1 Mercapto-alkanol flavor compounds GIVAUDAN SA 2004-03-11 US disclosed
US-6610346-B1 3- mercapto-2-methyl-butan-1-ol and/or 3-mercapto-3-methyl-hexan-1- ol, and the stereoisomers of each, are used to flavor products, such as foods and/or beverages. Methods for the preparation of both GIVAUDAN SCHWEIZ AG (CH) 2003-08-26 US disclosed
EP-1055667-A2 Mercapto alcohols as flavouring compounds Givaudan SA (CH) 2000-11-29 EP disclosed