Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808979 | 0.89 | PPID (0.45) | PPIDALOX5ABCB1SMN1; SMN2MAPT | |
| SCHEMBL5808973 | 0.89 | PPID (0.45) | PPIDALOX5ABCB1SMN1; SMN2MAPT | |
| SCHEMBL5795342 | 0.89 | PPID (0.45) | PPIDALOX5ABCB1SMN1; SMN2MAPT | |
| SCHEMBL6560435 | 0.87 | CA12 (0.43) | PPIDTDP1 | |
| Ethyl Acetate SCHEMBL6494884 | 0.85 | ALDH1A1 (0.43) | PPIDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4078833 | 0.84 | CA12 (0.43) | MAPTTDP1 | |
| SCHEMBL4078944 | 0.83 | TSHR (0.51) | SMN1; SMN2MAPTTDP1CYP4F2CYP4A11 | |
| SCHEMBL4071793 | 0.83 | SLC13A5 (0.49) | SMN1; SMN2 | |
| SCHEMBL6696645 | 0.83 | SLC13A5 (0.49) | SMN1; SMN2 | |
| SCHEMBL4071789 | 0.83 | SLC13A5 (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481961-B1 | PROCESS FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYLETHYL)HEXANOIC ACID AND ITS INTERMEDIATE | SUMITOMO CHEMICAL CO (JP) | 2009-11-25 | — | — | EP | disclosed |
| CN-100528828-C | Production method of racemiation3-hydroxy-3- (2-phenylethyl) hexanoic acid C1-6 alkyl ester | SUMIKA FINE CHEMICALS CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| EP-1894912-B1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | SUMITOMO CHEMICAL CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-1894912-B1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | SUMITOMO CHEMICAL CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090062346-A1 | DEUTERIUM-ENRICHED TIPRANAVIR | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090062346-A1 | DEUTERIUM-ENRICHED TIPRANAVIR | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| EP-1894912-A1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | Sumitomo Chemical Company, Limited (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1894912-A1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | Sumitomo Chemical Company, Limited (JP) | 2008-03-05 | — | — | EP | disclosed |
| CN-1982284-A | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO LTD (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1301244-C | Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2007-02-21 | — | — | CN | disclosed |
| US-7038075-B2 | Production method of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid C1-6 alkyl ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-02 | — | — | US | disclosed |
| CN-1617846-A | Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2005-05-18 | — | — | CN | disclosed |
| EP-1481961-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYLETHYL)HEXANOIC ACID AND ITS INTERMEDIATE | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040138496-A1 | Production method of (R)-3- hydroxy-3-(2-phenylethyl)hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| WO-2004052883-A2 | PROCESS FOR THE SEPARATION OF ENANTIOMERS | HONEYWELL INTERNATIONAL INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040110957-A1 | Process for the synthesis of an antiviral compound | HONEYWELL INTERNATIONAL, INC. (US) | 2004-06-10 | — | — | US | disclosed |
| US-6683207-B2 | RESOLUTION USING 1-AMINO-1-PHENYLETHANE DERIVATIVE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| US-20030176507-A1 | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| JP-2003112045-A | ACTIVATED ZINC, ITS USE, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING ETHYL 3-HYDROXY-3-(2- PHENYLETHYL)HEXANOATE USING THE SAME | SUMIKA FINE CHEMICALS CO LTD | 2003-04-15 | — | — | JP | disclosed |
| JP-2003112045-A | ACTIVATED ZINC, ITS USE, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING ETHYL 3-HYDROXY-3-(2- PHENYLETHYL)HEXANOATE USING THE SAME | SUMIKA FINE CHEMICALS CO LTD | 2003-04-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138496-A1 | Production method of (R)-3- hydroxy-3-(2-phenylethyl)hexanoic acid and intermediate thereof | HAAO, HPD, HAO2 | PPID 3280/4885ALOX5 109/4885ABCB1 1423/4885 |
| US-20040110957-A1 | Process for the synthesis of an antiviral compound | EIF2AK2, IRF3, RTF1 | PPID 3019/4885ALOX5 1693/4885ABCB1 4216/4885 |
| US-20030176507-A1 | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | HAAO, HPD, HAO2 | PPID 3238/4885ALOX5 96/4885ABCB1 1678/4885 |
| US-20090062346-A1 | DEUTERIUM-ENRICHED TIPRANAVIR | SAMHD1, NSD3, NSD1 | PPID 1424/4885ALOX5 3958/4885ABCB1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.