Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109279 | 0.89 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MEN1KMT2ADPP7 | |
| SCHEMBL647938 | 0.85 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MEN1KMT2ADPP7 | |
| SCHEMBL19392289 | 0.83 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1042604 | 0.83 | KMT2A (0.60) | ALDH1A1L3MBTL1MEN1KMT2ADPP7 | |
| SCHEMBL31073643 | 0.83 | MAPT (0.52) | HSP90AA1ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL31073637 | 0.83 | MAPT (0.52) | HSP90AA1ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL1041595 | 0.82 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1042326 | 0.80 | KMT2A (0.66) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL1041553 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MEN1KMT2ADPP7 | |
| SCHEMBL12509821 | 0.79 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MEN1KMT2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096771-A1 | BIARYL COMPOUNDS HAVING ACTIVITY AT THE 5HT5A RECEPTOR | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |