Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GPR68 | Q15743 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14058517 | 0.83 | ADORA2A (0.67) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL1149978 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL527618 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL19227719 | 0.80 | ADORA3 (0.62) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL855684 | 0.80 | ADORA3 (0.62) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL917182 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL28634836 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL3424387 | 0.80 | ADORA2A (0.90) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL27898 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL17840534 | 0.79 | NPSR1 (0.73) | ADORA2AADORA1ADORA3ADORA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |