Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GPR68 | Q15743 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | TPH1 | P17752 | 6/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197517 | 0.85 | NPSR1 (0.71) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6269189 | 0.85 | NPSR1 (0.71) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL527618 | 0.82 | ADORA2A (0.64) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL8410920 | 0.82 | NPSR1 (0.68) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL13140029 | 0.82 | NPSR1 (0.68) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL11664446 | 0.81 | NPSR1 (0.66) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL724054 | 0.81 | NPSR1 (0.66) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL14058517 | 0.80 | ADORA2A (0.67) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL4027047 | 0.80 | NPSR1 (0.64) | NPSR1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6975276 | 0.79 | ADORA2A (0.60) | NPSR1ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458116-B2 | Benzoguanamine compound having aminomethyl group, or salt thereof, and method for manufacturing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-10-04 | — | — | US | disclosed |
| US-20160176827-A1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP, OR SALT THEREOF, AND METHOD FOR MANUFACTURING THE SAME | MITSUBHIS GAS CHEMICAL COMPANY, INC. (JP) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176827-A1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP, OR SALT THEREOF, AND METHOD FOR MANUFACTURING THE SAME | BCAT2, GNMT, BCAT1 | NPSR1 677/4885ADORA2A 2030/4885ADORA1 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.