Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.60 |
| ▸ | UGCG | Q16739 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225543 | 0.88 | GHSR (0.62) | GHSRUGCGCYP3A4TACR1 | |
| SCHEMBL5224878 | 0.83 | GHSR (0.56) | GHSRUGCG | |
| SCHEMBL5231527 | 0.83 | GHSR (0.56) | GHSRUGCG | |
| SCHEMBL6694789 | 0.81 | GHSR (0.59) | GHSRUGCGCYP3A4 | |
| SCHEMBL6694103 | 0.81 | GHSR (0.61) | GHSRUGCGCYP3A4 | |
| SCHEMBL6692639 | 0.81 | GHSR (0.61) | GHSRUGCGCYP3A4 | |
| SCHEMBL6692638 | 0.81 | GHSR (0.61) | GHSRUGCGCYP3A4 | |
| SCHEMBL6698193 | 0.80 | GHSR (0.59) | GHSRUGCGCYP3A4 | |
| SCHEMBL6698196 | 0.80 | GHSR (0.59) | GHSRUGCGCYP3A4 | |
| SCHEMBL5226545 | 0.80 | GHSR (0.62) | GHSRUGCGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38524-E1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2004-06-01 | — | — | US | disclosed |
| US-6251902-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2001-06-26 | — | — | US | disclosed |