Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118705 | 0.91 | ADORA1 (0.74) | ADORA1ADORA2AKMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL6831577 | 0.85 | MEN1 (0.59) | ADORA1ADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL14796725 | 0.81 | ABL1 (0.47) | ADORA1ADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL30269692 | 0.81 | ABL1 (0.47) | ADORA1ADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL6832217 | 0.81 | ADORA1 (0.53) | ADORA1ADORA2AKMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL7466847 | 0.81 | ADORA1 (0.50) | ADORA1ADORA2AKMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL2492563 | 0.79 | HSP90AA1 (0.57) | ADORA1ADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL4582424 | 0.77 | ADORA1 (0.83) | ADORA1ADORA2AKMT2AGFER | |
| SCHEMBL23336394 | 0.76 | HSP90AA1 (0.54) | ADORA1ADORA2AHSP90AA1HSP90AB1PTK2 | |
| SCHEMBL5453984 | 0.76 | ADORA1 (1.00) | ADORA1ADORA2AKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099187-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM. CO. LTD. (KR) | 2004-11-18 | — | — | WO | disclosed |