SCHEMBL6832440

SCHEMBL6832440

CCN(CC)c1ccc2cc(C(=O)c3ccc(I)cc3)c(=O)oc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.79
MEN1 O00255 10/20 0.68
KMT2A Q03164 10/20 0.68
ALDH1A1 P00352 8/20 0.68
MAPT P10636 7/20 0.68
KDM4E B2RXH2 7/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
HPGD P15428 4/20 0.68
ATM Q13315 3/20 0.68
USP2 O75604 2/20 0.68
HSD17B10 Q99714 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C19 P33261 1/20 0.68
SLC16A3 O15427 1/20 0.68
ALOX15 P16050 1/20 0.68
SLC16A1 P53985 1/20 0.68
CYP19A1 P11511 1/20 0.57
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
STAT3 P40763 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363687 0.93 MAOB (0.86) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL304258 0.93 MAOB (0.86) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL2992592 0.89 MAOB (0.84) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL195935 0.89 MAOB (0.80) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL30785604 0.88 MAOB (1.00) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL52729 0.88 MAOB (1.00) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL51872 0.88 MEN1 (0.82) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL9321949 0.87 MAOB (0.98) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL27459448 0.87 MAOB (0.77) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL6836135 0.87 SLC16A3 (0.66) MAOBMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US claimed
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-20040198859-A1 Photopolymerization systems and their use NGUYEN CHAU K (US) 2004-10-07 US disclosed
EP-0672953-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 2003-01-15 EP disclosed
EP-0730201-B1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2001-05-09 EP disclosed
US-6045953-A COMPRISES A SUBSTRATE, A PHOTOSENSITIVE LAYER FORMED ON THE SUBSTRATE BY COATING A PHOTOSENSITIVE SOLUTION CONTAINING AN ALICYCLIC, SOLVENT SOLUBLE, CATIONIC POLYMERIZABLE EPOXY RESIN AND AN ACRYLATE POLYMER TOPPAN PRINTING CO., LTD. (JP) 2000-04-04 US disclosed
EP-0697631-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 1998-06-10 EP disclosed
US-5698345-A CATIONIC POLYMERIZATION OF THERMOSETTING EPOXY OLIGOMER TOPPAN PRINTING CO., LTD. (JP) 1997-12-16 US disclosed
EP-0697631-A1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1996-02-21 EP disclosed
EP-0672953-A2 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1995-09-20 EP disclosed
US-4948694-A CONTAINING PHOTOINITIATOR COMPRISING CAMPHORQUINONE AND COUMARIN DERIVATIVE; SENSITIVITY, STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1990-08-14 US disclosed
US-4868092-A SENSITIVE TO VISIBLE LIGHT, XANTHENE DYE INITIATOR NIPPON PAINT CO., LTD. (JP) 1989-09-19 US disclosed
EP-0276016-A2 Photopolymerizable composition Nippon Paint Co., Ltd. (JP) 1988-07-27 EP disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed
US-4152159-A ACRYLIC ESTER POLYMERS EASTMAN KODAK COMPANY (US) 1979-05-01 US disclosed