SCHEMBL2992592

SCHEMBL2992592

CCN(CC)c1ccc2cc(C(=O)c3ccc(C(=O)O)cc3)c(=O)oc2c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.84
ALDH1A1 P00352 6/20 0.77
SMN1; SMN2 Q16637 4/20 0.77
HPGD P15428 4/20 0.77
KDM4E B2RXH2 4/20 0.77
SLC16A3 O15427 2/20 0.77
HSD17B10 Q99714 2/20 0.77
ALOX15 P16050 1/20 0.77
SLC16A1 P53985 1/20 0.77
MEN1 O00255 8/20 0.70
KMT2A Q03164 8/20 0.70
MAPT P10636 6/20 0.70
ATM Q13315 3/20 0.70
USP2 O75604 2/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2C19 P33261 1/20 0.70
CYP19A1 P11511 1/20 0.59
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
STAT3 P40763 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363687 0.94 MAOB (0.86) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL304258 0.94 MAOB (0.86) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL30785604 0.92 MAOB (1.00) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL52729 0.92 MAOB (1.00) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL9321949 0.91 MAOB (0.98) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL195935 0.91 MAOB (0.80) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL6832440 0.89 MAOB (0.79) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL51872 0.89 MEN1 (0.82) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL27459448 0.88 MAOB (0.77) MAOBALDH1A1SMN1; SMN2HPGDKDM4E
SCHEMBL42693 0.87 ALDH1A1 (1.00) MAOBALDH1A1SMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3427716-B1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2021-11-24 EP disclosed
CN-108697586-B Photopolymerization initiator and photocurable composition 株式会社德山齿科 2021-07-06 CN disclosed
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
EP-3427716-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2019-01-16 EP disclosed
US-20130071804-A1 Adhesive for Teeth-Straightening Members TOKUYAMA DENTAL CORPORATION (JP) 2013-03-21 US disclosed
EP-1249221-B1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2010-10-13 EP disclosed
US-20100184882-A1 ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS NIHON UNIVERSITY (JP) 2010-07-22 US disclosed
EP-2149360-A1 ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS Nihon University (JP) 2010-02-03 EP disclosed
US-6759449-B2 NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR TOKUYAMA DENTAL CORPORATION (JP) 2004-07-06 US disclosed
US-20030050359-A1 Dental adhesive composition TOKUYAMA DENTAL CORPORATION (JP) 2003-03-13 US disclosed
EP-0896043-B1 Adhesive TOKUYAMA CORP (JP) 2002-10-23 EP disclosed
EP-1249221-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2002-10-16 EP disclosed
EP-0738928-B1 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORP (JP) 2001-06-20 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION INO80C, JAK2, PCNA MAOB 944/4885ALDH1A1 1336/4885SMN1; SMN2 4605/4885
US-20030050359-A1 Dental adhesive composition CAD, ASIC1, CD44 MAOB 4157/4885ALDH1A1 114/4885SMN1; SMN2 3961/4885
US-20100184882-A1 ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS ICAM1, TLN1, COIL MAOB 1784/4885ALDH1A1 151/4885SMN1; SMN2 3208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.