SCHEMBL195935

SCHEMBL195935

CCN(CC)c1ccc2cc(C(=O)c3ccc(N(C)C)cc3)c(=O)oc2c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.80
MEN1 O00255 9/20 0.70
KMT2A Q03164 9/20 0.70
ALDH1A1 P00352 7/20 0.70
MAPT P10636 6/20 0.70
KDM4E B2RXH2 6/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
HPGD P15428 3/20 0.70
ATM Q13315 2/20 0.70
SLC16A3 O15427 2/20 0.70
USP2 O75604 1/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2C19 P33261 1/20 0.70
ALOX15 P16050 1/20 0.70
SLC16A1 P53985 1/20 0.70
HSD17B10 Q99714 1/20 0.70
CYP19A1 P11511 1/20 0.59
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
STAT3 P40763 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459448 0.95 MAOB (0.77) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL304258 0.94 MAOB (0.86) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL29363687 0.94 MAOB (0.86) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL9771949 0.91 MEN1 (0.74) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL2992592 0.91 MAOB (0.84) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL11225033 0.90 SLC16A3 (0.72) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL6832440 0.89 MAOB (0.79) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL52729 0.89 MAOB (1.00) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL30785604 0.89 MAOB (1.00) MAOBMEN1KMT2AALDH1A1MAPT
SCHEMBL28996614 0.89 MAOB (0.78) MAOBMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
EP-3162868-B1 THERMAL BASE GENERATOR, THERMOSETTING RESIN COMPOSITION, CURED FILM, CURED FILM MANUFACTURING METHOD, AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2022-10-05 EP disclosed
EP-3593786-B1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORP (JP) 2022-05-18 EP disclosed
CN-107966877-B Composition for color filter 富士胶片株式会社 2022-04-12 CN disclosed
US-11273104-B2 Photocurable composition and dental restoration filling material TOKUYAMA DENTAL CORPORATION (JP) 2022-03-15 US disclosed
EP-3427716-B1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2021-11-24 EP disclosed
CN-108697586-B Photopolymerization initiator and photocurable composition 株式会社德山齿科 2021-07-06 CN disclosed
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
EP-3124548-B1 MICROLENS COMPRING A TRANSPARENT FILM AND SOLID-STATE IMAGING DEVICE USING THE SAME FUJIFILM CORP (JP) 2020-12-02 EP disclosed
CN-107709407-B Polyimide precursor composition, photosensitive resin composition, cured film, method for producing cured film, semiconductor device, and method for producing polyimide precursor composition 富士胶片株式会社 2020-11-17 CN disclosed
US-4619890-A BENZENE OR CYCLOHEXANE ACRYLIC ESTER EASTMAN KODAK COMPANY (US) 1986-10-28 US disclosed
EP-0129234-A1 Electrophotographic elements having barrier layers of crosslinked polymers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-12-27 EP disclosed
US-4485161-A Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents EASTMAN KODAK COMPANY (US) 1984-11-27 US disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4342151-A PHOTOPOLYMERIZING THE NEGATIVE-WORKING RESIST EASTMAN KODAK COMPANY (US) 1982-08-03 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US disclosed
US-4247623-A INTEGRATED CIRCUITS EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273104-B2 Photocurable composition and dental restoration filling material H1-0, REV1, RER1 MAOB 938/4885MEN1 1122/4885KMT2A 3632/4885
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION INO80C, JAK2, PCNA MAOB 944/4885MEN1 2856/4885KMT2A 444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.