Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7963936 | 0.98 | MAPT (0.51) | MAPTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL728274 | 0.86 | CA12 (0.47) | MAPTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL29411874 | 0.81 | MEN1 (0.50) | MAPTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL24151505 | 0.78 | MAPT (0.47) | MAPTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL1465116 | 0.78 | MEN1 (0.50) | MAPTL3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL2857440 | 0.77 | MAPT (0.62) | MAPTHPGDMEN1KMT2AHTT | |
| SCHEMBL31497260 | 0.77 | KMT2A (0.51) | MAPTHPGDMEN1KMT2ACA12 | |
| SCHEMBL4033840 | 0.77 | TGM2 (0.50) | L3MBTL1HPGDMEN1KMT2ACA12 | |
| SCHEMBL1220014 | 0.77 | CYP3A4 (0.47) | MAPTMEN1KMT2ACA12CA9 | |
| SCHEMBL31591724 | 0.77 | CYP3A4 (0.47) | MAPTMEN1KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039014-A1 | Methods and compounds for treating depression and other disorders | NPS PHARMACEUTICALS, INC. | 2004-02-26 | — | — | US | disclosed |
| EP-1096926-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002551-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0145401-B1 | PHOTOCONDUCTIVE DEVICE CONTAINING NOVEL BENZYL FLUORINATED SQUARAINE COMPOUNDS | XEROX CORPORATION (US) | 1987-12-09 | — | — | EP | disclosed |
| US-4644082-A | Photoconductive devices containing novel benzyl fluorinated squaraine compositions | XEROX CORPORATION (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0145401-A2 | Photoconductive device containing novel benzyl fluorinated squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4508803-A | Photoconductive devices containing novel benzyl fluorinated squaraine compositions | XEROX CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039014-A1 | Methods and compounds for treating depression and other disorders | GRIN1, GRIN2C, GRIN3B | MAPT 2600/4885L3MBTL1 4595/4885HPGD 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.