SCHEMBL2857440

SCHEMBL2857440

C=CCNc1cccc(C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.62
CYP1A2 P05177 2/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
HTT P42858 1/20 0.62
HPGD P15428 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TP53 P04637 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2857434 0.98 MAPT (0.60) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL728274 0.86 CA12 (0.47) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8628395 0.79 THRB (0.44) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL10727579 0.78 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8798563 0.77 EGFR (0.66) MAPTHTTHPGDTP53MEN1
SCHEMBL9396667 0.77 MAPT (0.75) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8373327 0.77 MAPT (1.00) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29612398 0.77 MAPT (0.75) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4033840 0.77 TGM2 (0.50) CYP1A2CYP2C19HTTHPGDTDP1
SCHEMBL6832452 0.77 MAPT (0.52) MAPTHTTHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798090-A Palladium-catalyzed synthesis method of N-monoallylamine derivative 深圳职业技术大学 2025-04-11 CN disclosed
CN-106478543-B Benzisothiazole dye monomer compound and intermediate, preparation method and application thereof 浙江闰土研究院有限公司 2020-03-06 CN disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-8841396-B2 Ethylene-α-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-23 US disclosed
US-20130324691-A1 Ethylene-a-Olefin Copolymer and Article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-05 US disclosed
US-20130005930-A1 ETHYLENE-alpha-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-03 US disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
EP-0942006-B1 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORP (JP) 2003-06-04 EP disclosed
EP-0849292-B1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORP (JP) 2002-08-21 EP disclosed
US-20020091254-A1 Stabilizing and/or lowering the color number of alkenyl compounds BASF AKTIENGESELLSCHAFT (DE) 2002-07-11 US disclosed
US-6384216-B1 CARRYING OUT TWO DISTILLATIONS IN WHICH THE PURIFIED ALKENYL COMPOUNDS OBTAINED FROM GAS PHASE BY CONDENSATION, WHERE THE TIME BETWEEN FIRST DISTILLATION AFTER SYNTHESIS OF ALKENYL COMPOUNDS AND FURTHER DISTILLATION BASF AKTIENGESELLSCHAFT (DE) 2002-05-07 US disclosed
US-6372681-B1 METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2002-04-16 US disclosed
US-20020038059-A1 PURIFICATION OF ALKENYL COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-03-28 US disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091254-A1 Stabilizing and/or lowering the color number of alkenyl compounds SOD1, NOX4, CAT MAPT 673/4885CYP1A2 1666/4885CYP3A4 764/4885
US-20020038059-A1 PURIFICATION OF ALKENYL COMPOUNDS TPR, AGPAT5, PCNA MAPT 1610/4885CYP1A2 2986/4885CYP3A4 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.