Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 4/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618897 | 1.00 | PTGS1 (0.55) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL31260122 | 0.82 | GRIK1 (0.46) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL31670693 | 0.82 | GRIK1 (0.46) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL7366965 | 0.81 | GRIK1 (0.50) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL564563 | 0.81 | GRIK1 (0.50) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL3145928 | 0.81 | GRIK1 (0.50) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL3044802 | 0.81 | GRIK1 (0.50) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| Aspartic Acid SCHEMBL28538562 | 0.80 | GRIK1 (0.54) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL23829840 | 0.79 | GRIK1 (0.48) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 | |
| SCHEMBL6598328 | 0.79 | GRIK1 (0.48) | PTGS1SLC7A11GRIK1GRIK2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680311-A | Method for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1987-07-14 | — | — | US | claimed |
| EP-0202778-A2 | Use of (S)-2-amino-5-hydroxy-4-oxopentanoic acid for the preparation of a medicament for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-26 | — | — | EP | claimed |
| JP-61243018-A | — | — | None | — | — | JP | disclosed |
| US-9012567-B2 | Supramolecular polymers and compositions containing said polymers | RHODIA OPERATIONS (FR) | 2015-04-21 | — | — | US | disclosed |
| US-8986399-B2 | Treating lignocellulosic materials | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2015-03-24 | — | — | US | disclosed |
| US-20120297555-A1 | TREATING LIGNOCELLULOSIC MATERIALS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2012-11-29 | — | — | US | disclosed |
| US-20120289652-A1 | SUPRAMOLECULAR POLYMERS AND COMPOSITIONS CONTAINING SAID POLYMERS | RHODIA OPERATIONS (FR) | 2012-11-15 | — | — | US | disclosed |
| US-6743432-B1 | MEMBRANE HAVING LOW ADSORPTIVITY FOR PROTEIN; HOMO- OR CO-POLYMER OF FLUORINE-CONTAINING MONOMER INCLUDING HYDROPHILIC GROUP, HYDROPHILIZED POLYSULFONE INCORPORATING WETTING AGENT, HYDROPHILIZED CELLULOSE DERIVATIVE | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2004-06-01 | — | — | US | disclosed |
| EP-0747092-B1 | Matrix for iontophoresis | HISAMITSU PHARMACEUTICAL CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-0748636-B1 | Interface for iontophoresis | HISAMITSU PHARMACEUTICAL CO (JP) | 2003-08-27 | — | — | EP | disclosed |
| EP-0950407-B1 | The use of a GP IIb/IIIa antagonist for the manufacture of a medicament suitable for transdermal application by iontophoresis | HISAMITSU PHARMACEUTICAL CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-0638588-A1 | Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0604945-A1 | TAN-1511, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0604957-A1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0202778-A3 | Use of (S)-2-amino-5-hydroxy-4-oxopentanoic acid for the preparation of a medicament for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4680311-A | Method for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4680311-A | Method for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0202778-A2 | Use of (S)-2-amino-5-hydroxy-4-oxopentanoic acid for the preparation of a medicament for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-26 | — | — | EP | disclosed |
| EP-0202778-A2 | Use of (S)-2-amino-5-hydroxy-4-oxopentanoic acid for the preparation of a medicament for the treatment of systemic mycosis | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-26 | — | — | EP | disclosed |
| JP-S61243018-A | REMEDY FOR MYCOSIS | TAISHO PHARMACEUT CO LTD | 1986-10-29 | — | — | JP | disclosed |