SCHEMBL6598328

SCHEMBL6598328

[NH]CC(=O)CC(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 9/20 0.48
GRIK2 Q13002 6/20 0.48
GRM1 Q13255 2/20 0.48
GRM2 Q14416 2/20 0.48
SLC7A5 Q01650 1/20 0.46
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
GGT1 P19440 4/20 0.43
SLC1A1 P43005 4/20 0.43
GRIA4 P48058 4/20 0.42
GRIK3 Q13003 4/20 0.42
GRIK5 Q16478 4/20 0.42
SLC1A3 P43003 3/20 0.41
SLC1A2 P43004 3/20 0.41
GRIA2 P42262 3/20 0.41
GRIA1 P42261 2/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618897 0.79 PTGS1 (0.55) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL6832737 0.79 PTGS1 (0.55) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL564563 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL3145928 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL3044802 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL7366965 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL23829840 0.75 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL3286497 0.75 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL4524329 0.75 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL4445542 0.75 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980366-B1 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 2004-06-09 EP claimed