SCHEMBL6832866

SCHEMBL6832866

CCc1cccc2c1OCCC2=O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 9/20 0.41
LTB4R2 Q9NPC1 9/20 0.41
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
MAOB P27338 3/20 0.37
MAOA P21397 1/20 0.37
GRM5 P41594 2/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3992891 0.81 XPO1 (0.44) LTB4RLTB4R2ALDH1A1MAPTKDM4E
SCHEMBL19744350 0.79 MAPT (0.43) ALDH1A1MAOBMAOAGRM5MAPT
SCHEMBL31170819 0.79 MAPT (0.43) ALDH1A1MAOBMAOAGRM5MAPT
SCHEMBL12467354 0.77 PARP1 (0.51) ALDH1A1MAPTGABRA1GABRB2KDM4E
SCHEMBL6836952 0.75 MAOA (0.46) LTB4RLTB4R2ALDH1A1MAOBMAOA
SCHEMBL3993011 0.75 LMNA (0.44) ALDH1A1MAOBMAOAGRM5MAPT
SCHEMBL768960 0.75 MAPT (0.46) MAOBMAOAGRM5MAPTLMNA
SCHEMBL1265527 0.75 CYP19A1 (0.46) MAOBMAOAGRM5MAPTLMNA
SCHEMBL29222703 0.75 MAOB (0.39) LTB4RLTB4R2ALDH1A1MAOBMAOA
SCHEMBL2370234 0.75 MAOB (0.39) ALDH1A1MAOBMAOAGRM5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed