Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970288 | 0.86 | CYP2C9 (0.59) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL226013 | 0.86 | ESR1 (0.64) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL18630379 | 0.85 | CYP2C9 (0.57) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL92890 | 0.81 | CYP2C9 (0.68) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL29836296 | 0.81 | CYP2C9 (0.68) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL9319647 | 0.79 | CYP2C9 (0.65) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL27810275 | 0.79 | CYP2C9 (0.65) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL561925 | 0.78 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL29912683 | 0.78 | CYP2C19 (0.53) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL11698053 | 0.78 | CYP2C9 (0.63) | CYP2C9CYP2C19CYP1A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747170-B2 | LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | HAYAKAWA KUNIO (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6555705-B1 | A supported thermosensitive recording layer containing a leuco dye and a color developer to induce color in the leuco dye upon heating; using 4-(2- or 4-phenoxyethoxy- or butoxy phthalic acid; image stability; oil, fat repellant | RICOH COMPANY, LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| US-6180560-B1 | LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY | RICOH COMPANY, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0612628-B1 | Thermosensitive recording material using phthalic acid derivatives | RICOH KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5482912-A | DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES | RICOH COMPANY, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0612628-A1 | Thermosensitive recording material using phthalic acid derivatives | Ricoh Company, Ltd (JP) | 1994-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071187-A1 | Thermosensitive recording material and color developer compound therefor | LRBA, THEM6, GOT1 | CYP2C9 1418/4885CYP2C19 1875/4885CYP1A2 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.