SCHEMBL6833068

SCHEMBL6833068

N#Cc1ccc(NC(=O)c2noc3ccc(NCC4CC4)cc23)c(C(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.39
CDK2 P24941 1/20 0.37
LIPC P11150 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
PDE10A Q9Y233 2/20 0.36
BCL6 P41182 1/20 0.36
CETP P11597 5/20 0.35
HIF1A Q16665 3/20 0.35
VNN1 O95497 2/20 0.35
MAP2K1 Q02750 1/20 0.35
PPARG P37231 1/20 0.34
KDM4C Q9H3R0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833108 0.87 HIF1A (0.39) ALBCDK2PDE10ACETPHIF1A
SCHEMBL6833569 0.86 CDK2 (0.40) ALBCDK2HIF1AMAP2K1PPARG
SCHEMBL6818719 0.86 ALB (0.39) ALBCDK2LIPCLIPGPDE10A
SCHEMBL6830652 0.84 ALB (0.44) ALBCDK2PDE10ACETPHIF1A
SCHEMBL6835810 0.84 ALB (0.39) ALBPDE10ACETPHIF1A
SCHEMBL6833798 0.83 ALB (0.37) ALBCDK2HIF1APPARG
SCHEMBL6835869 0.83 HIF1A (0.41) ALBHIF1APPARG
SCHEMBL6834155 0.82 F2 (0.50) ALBHIF1A
SCHEMBL6834064 0.81 ALB (0.42) ALBHIF1A
SCHEMBL6833806 0.81 KDM4C (0.45) ALBCETPHIF1AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALB 1417/4885CDK2 4509/4885LIPC 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.