Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329921 | 0.79 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL16619760 | 0.79 | HDAC2 (0.42) | ALDH1A1TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL5932677 | 0.75 | HDAC2 (0.42) | ALDH1A1TSHRHSD17B10HDAC4HDAC2 | |
| SCHEMBL3459504 | 0.73 | HDAC4 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL5932198 | 0.72 | HDAC2 (0.44) | ALDH1A1TSHRHSD17B10HDAC4HDAC2 | |
| SCHEMBL5932189 | 0.72 | HDAC2 (0.44) | ALDH1A1TSHRHSD17B10HDAC4HDAC2 | |
| SCHEMBL25095364 | 0.71 | HDAC2 (0.42) | ALDH1A1TSHRHSD17B10HDAC4HDAC2 | |
| SCHEMBL6559546 | 0.71 | HDAC4 (0.42) | ALDH1A1HSD17B10HDAC4HDAC2HDAC8 | |
| SCHEMBL5932684 | 0.71 | HDAC2 (0.42) | ALDH1A1TSHRHSD17B10HDAC4HDAC2 | |
| SCHEMBL11874918 | 0.71 | HDAC4 (0.39) | ALDH1A1TSHRHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | PARKER HUGHES INSTITUTE | 2004-09-02 | — | — | US | disclosed |
| US-6774139-B1 | CONTRACEPTIVES | PARKER HUGHES INSTITUTE | 2004-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | ZP1, NASP, SAMHD1 | ALDH1A1 1417/4885TP53 3635/4885TYR 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.