SCHEMBL16619760

SCHEMBL16619760

NC(=O)NC1=CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 6/20 0.42
HDAC4 P56524 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC1 Q13547 5/20 0.35
HDAC3 O15379 3/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
CTSK P43235 1/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PEPD P12955 1/20 0.33
CCR2 P41597 1/20 0.33
NPC1 O15118 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5932198 0.81 HDAC2 (0.44) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL5932189 0.81 HDAC2 (0.44) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL329921 0.79 HDAC4 (0.34) HDAC2HDAC4HDAC8HDAC6KDM1A
SCHEMBL6559546 0.79 HDAC4 (0.42) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL5932677 0.79 HDAC2 (0.42) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL25095364 0.79 HDAC2 (0.42) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL6833727 0.79 ALDH1A1 (0.34) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL5932684 0.79 HDAC2 (0.42) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL11874918 0.79 HDAC4 (0.39) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL11874913 0.75 HDAC4 (0.39) HDAC2HDAC4HDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052473-B1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL SCIENT IND RES (IN) 2018-01-17 EP claimed
US-9522922-B2 Process for the preparation of intermediate for the preparation of oseltamivir phosphate COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-12-20 US claimed
EP-3052473-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2016-08-10 EP claimed
US-20160222029-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-08-04 US claimed
WO-2015049700-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-04-09 WO claimed
CN-115707465-B Application of dimethylaminomichelia lactone and derivatives thereof in preparation of drugs for improving blood brain barrier permeability 天津尚德药缘科技股份有限公司 2024-06-07 CN disclosed
CN-114409880-A Preparation method of recyclable bio-based polyester 青岛科技大学 2022-04-29 CN disclosed
EP-3052473-B1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL SCIENT IND RES (IN) 2018-01-17 EP disclosed
US-9522922-B2 Process for the preparation of intermediate for the preparation of oseltamivir phosphate COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-12-20 US disclosed
EP-3052473-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2016-08-10 EP disclosed
US-20160222029-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-08-04 US disclosed
WO-2015049700-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160222029-A1 A PROCESS FOR THE PREPARATION OF INTERMEDIATE FOR THE PREPARATION OF OSELTAMIVIR PHOSPHATE OSGEP, CYP2B6, CYP2F1 HDAC2 2775/4885HDAC4 4505/4885HDAC8 4616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.