SCHEMBL6834058

SCHEMBL6834058

Cc1sc(C(=O)Nc2ccc(Br)cc2C(=O)O)cc1S(=O)(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
HSD17B10 Q99714 2/20 0.46
POLB P06746 2/20 0.46
GBA1 P04062 1/20 0.46
GAA P10253 1/20 0.46
SMPD1 P17405 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 1/20 0.44
ALB P02768 1/20 0.44
MPO P05164 1/20 0.43
LMNA P02545 1/20 0.42
SERPINE1 P05121 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833972 0.89 ALB (0.44) MAPTMEN1KMT2AHSD17B10POLB
SCHEMBL6830625 0.85 MAPT (0.48) MAPTMEN1KMT2AHSD17B10POLB
SCHEMBL6352341 0.85 TP53 (0.54) MAPTMEN1KMT2AHSD17B10POLB
SCHEMBL6353827 0.84 ALB (0.52) MAPTMEN1KMT2APOLBGBA1
SCHEMBL6834271 0.84 MEN1 (0.49) MAPTMEN1KMT2APOLBSMN1; SMN2
SCHEMBL6357053 0.83 ALB (0.51) MAPTMEN1KMT2AHSD17B10POLB
SCHEMBL6356455 0.82 HSD17B10 (0.58) MAPTMEN1KMT2AHSD17B10POLB
SCHEMBL6352316 0.82 ALB (0.67) SMN1; SMN2ALBLMNAHTTTP53
SCHEMBL6833566 0.81 MAPT (0.51) MAPTMEN1KMT2ASMN1; SMN2ALB
SCHEMBL6358680 0.81 ALB (0.52) MAPTMEN1KMT2AHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 MAPT 4759/4885MEN1 4132/4885KMT2A 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.