SCHEMBL6834332

SCHEMBL6834332

C=C(C)C(=O)Nc1ccc(S)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.62
TDP1 Q9NUW8 3/20 0.51
L3MBTL1 Q9Y468 5/20 0.46
POLB P06746 3/20 0.46
RECQL P46063 2/20 0.46
BLM P54132 2/20 0.46
BAZ1A Q9NRL2 1/20 0.46
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CA12 O43570 1/20 0.41
BRD4 O60885 1/20 0.41
NR1I2 O75469 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MB P02144 1/20 0.41
CYP1A1 P04798 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439393 0.89 RXFP1 (0.74) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL17084525 0.83 RXFP1 (0.67) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL959539 0.82 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL124216 0.82 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL7800028 0.80 TDP1 (0.66) RXFP1TDP1L3MBTL1POLBALDH1A1
Hydrochloric Acid SCHEMBL7460090 0.80 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL17299114 0.80 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL8164496 0.80 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL5071228 0.80 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL3298240 0.80 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10285914-B2 Bonding method, bonding kit, and bonding material TOKUYAMA DENTAL CORPORATION (JP) 2019-05-14 US disclosed
US-20170156991-A1 BONDING METHOD, BONDING KIT, AND BONDING MATERIAL TOKUYAMA DENTAL CORPORATION (JP) 2017-06-08 US disclosed
EP-1699790-B1 SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2012-09-05 EP disclosed
US-20080038669-A1 NON-TRULY-SPHERICAL HIGH-MOLECULAR FINE PARTICLES, PROCESS FOR PRODUCING THE SAME, INKJET INK COMPOSITION CONTAINING FINE PARTICLES, LITHOGRAPHIC PRINTING PLATE USING THE SAME, PROCESS FOR PRODUCING PRINTING PLATE, AND ELECTROPHORETIC PARTICLES-CONTAINING COMPOSITION CONTAINING FINE PARTICLES FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-6818680-B2 ACTINIC RADIATION OR ELECTRON BEAM CURABLE MALEIMIDE OLIGOMER, MULTIFUNCTIONAL THIOL, AND POLYMERIZABLE (METH)ACRYLATE OR THIO(METH)ACRYLATE COMPOUND; GOLD SEALANTS; NONHYDROLYZING, OXIDATION RESISTANCE CORNING INCORPORATED 2004-11-16 US disclosed
US-20040072933-A1 Photopolymerization; curing using electron beams, actinic radiation; polymer or oligomer containing maleimide end groups; joining optical communication cables CORNING INCORPORATED 2004-04-15 US disclosed
US-5670657-A DISULFIDE CYCLIC COMPOUND FOR PRECIOUS METAL ADHESIVES KABUSHIKI KAISHA SHOFU (JP) 1997-09-23 US disclosed
EP-0592972-A2 Resist coated metal- or semiconductor-substrate having a stable resist-substrate adhesion INSTITUT FÜR MIKROTECHNIK MAINZ GmbH (DE) 1994-04-20 EP disclosed
EP-0348166-B1 Adhesive composition containing a thiocarboxylic acid or a derivative thereof KURARAY CO (JP) 1994-04-20 EP disclosed
EP-0310919-B1 Adhesive composition for biomaterial use DAIKIN IND LTD (JP) 1994-01-05 EP disclosed
US-5254198-A Water-resistant, high strength bond; dental applications KURARAY CO., LTD. (JP) 1993-10-19 US disclosed
US-5186783-A High strength bonding, dentistry KURARAY CO., LTD. (JP) 1993-02-16 US disclosed
EP-0277413-B1 ADHESIVE PARTICULARLY FOR DENTAL USE KURARAY CO., LTD. (JP) 1992-04-22 EP disclosed
US-5085726-A Dentistry KURARAY CO., LTD. (JP) 1992-02-04 US disclosed
US-5064495-A And a copolymerizable olefinic monomer KURARAY COMPANY, LIMITED (JP) 1991-11-12 US disclosed
US-5061184-A Fluorine-containing acrylic esters; dentistry DAIKIN INDUSTRIES, LTD. (JP) 1991-10-29 US disclosed
EP-0348166-A2 Adhesive composition containing a thiocarboxylic acid or a derivative thereof KURARAY CO., LTD. (JP) 1989-12-27 EP disclosed
EP-0310919-A2 Adhesive composition for biomaterial use DAIKIN INDUSTRIES, LIMITED (JP) 1989-04-12 EP disclosed
EP-0277413-A2 Adhesive particularly for dental use KURARAY CO., LTD. (JP) 1988-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10285914-B2 Bonding method, bonding kit, and bonding material SUV39H1, SUV39H2, EZH1 RXFP1 4618/4885TDP1 2894/4885L3MBTL1 1853/4885
US-20170156991-A1 BONDING METHOD, BONDING KIT, AND BONDING MATERIAL SUV39H1, SUV39H2, EZH1 RXFP1 4618/4885TDP1 2894/4885L3MBTL1 1853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.