Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.67 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.46 |
| ▸ | GCGR | P47871 | 11/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | FRK | P42685 | 3/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836929 | 0.86 | NPY5R (0.69) | NPY5RKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6835195 | 0.85 | NPY5R (0.48) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6835539 | 0.85 | NPY5R (0.67) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6835180 | 0.82 | NPY5R (0.69) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6836970 | 0.82 | NPY5R (0.64) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6834518 | 0.81 | NPY5R (0.68) | NPY5RKDM4EHPGDLMNAMAPT | |
| SCHEMBL6835211 | 0.73 | NPY5R (0.66) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6835188 | 0.72 | NPY5R (0.61) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6835859 | 0.71 | NPY5R (0.69) | NPY5RMAPK14KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6567519 | 0.71 | NPY5R (0.49) | NPY5RMAPK14KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885MAPK13 4148/4885MAPK12 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.