Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835188 | 0.84 | NPY5R (0.61) | NPY5RKMT2AMAPK13MAPK12MAPK11 | |
| SCHEMBL6836970 | 0.75 | NPY5R (0.64) | NPY5RKDM4EALDH1A1MAPK13MAPK12 | |
| SCHEMBL6834673 | 0.73 | NPY5R (0.67) | NPY5RKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL6835195 | 0.73 | NPY5R (0.48) | NPY5RKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL6835539 | 0.73 | NPY5R (0.67) | NPY5RKDM4EKMT2AMAPK13MAPK12 | |
| SCHEMBL6836929 | 0.72 | NPY5R (0.69) | NPY5RKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL6835859 | 0.72 | NPY5R (0.69) | NPY5RKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL6831691 | 0.72 | NPY5R (0.66) | NPY5RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6835180 | 0.71 | NPY5R (0.69) | NPY5RMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6834506 | 0.70 | NPY5R (0.48) | NPY5RKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014753-A1 | Novel interleukin-1beta converting enzyme inhibitors | THE PROCTER & GAMBLE COMPANY | 2004-01-22 | — | — | US | claimed |
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885KDM4E 3547/4885MEN1 1176/4885 |
| US-20040014753-A1 | Novel interleukin-1beta converting enzyme inhibitors | IL1B, IL1RN, IL1R1 | NPY5R 1700/4885KDM4E 3067/4885MEN1 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.