Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835859 | 0.86 | NPY5R (0.69) | NPY5RCYP11B1KDM4EMAPTNPC1 | |
| SCHEMBL6834673 | 0.86 | NPY5R (0.67) | NPY5RKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6831691 | 0.84 | NPY5R (0.66) | NPY5RCYP11B1KDM4EMAPTNPC1 | |
| SCHEMBL6834518 | 0.79 | NPY5R (0.68) | NPY5RKDM4EMAPTNPC1HPGD | |
| SCHEMBL6834619 | 0.73 | NPY5R (0.53) | NPY5RCYP11B1TDO2CYP11B2 | |
| SCHEMBL6835211 | 0.72 | NPY5R (0.66) | NPY5RCYP11B1KDM4EMAPTNPC1 | |
| SCHEMBL6835539 | 0.71 | NPY5R (0.67) | NPY5RKDM4ENPC1RAB9ACYP11B2 | |
| SCHEMBL6835195 | 0.71 | NPY5R (0.48) | NPY5RKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6835188 | 0.71 | NPY5R (0.61) | NPY5RNPC1RAB9AKMT2A | |
| SCHEMBL6836970 | 0.70 | NPY5R (0.64) | NPY5RCYP11B1KDM4EALDH1A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885CYP11B1 67/4885TDO2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.