SCHEMBL6834824

SCHEMBL6834824

O=C(OO)C1CC2C=CC1CC2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 4/20 0.36
POLB P06746 3/20 0.34
APEX1 P27695 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KMT2A Q03164 2/20 0.33
RAB9A P51151 1/20 0.33
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
ESR2 Q92731 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11801332 0.83 KDM4E (0.42) KDM4ELMNAALDH1A1POLBKMT2A
SCHEMBL13956720 0.80 KDM4E (0.36) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL14420618 0.80 ALDH1A1 (0.39) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL7641822 0.79 ALDH1A1 (0.36) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL16728405 0.79 ALDH1A1 (0.39) ALDH1A1POLBAPEX1TDP1KMT2A
SCHEMBL19387893 0.79 ALDH1A1 (0.39) ALDH1A1POLBAPEX1TDP1KMT2A
SCHEMBL29928799 0.79 ALDH1A1 (0.39) ALDH1A1POLBAPEX1TDP1KMT2A
SCHEMBL20548051 0.78 POLB (0.48) KDM4ELMNAPOLBAPEX1TDP1
SCHEMBL22361971 0.78 POLB (0.48) KDM4ELMNAPOLBAPEX1TDP1
SCHEMBL6811019 0.78 KDM4E (0.42) KDM4ELMNAALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753128-B2 BLOCKING ACID GENERATION DURING PHOTOLITHOGRAPHY HYNIX SEMICONDUCTOR INC. (KR) 2004-06-22 US disclosed
US-20030082481-A1 Photoresist additive for preventing acid migration and photoresist composition comprising the same HYNIX SEMICONDUCTOR INC. (KR) 2003-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082481-A1 Photoresist additive for preventing acid migration and photoresist composition comprising the same RARG, ELMO1, COL2A1 KDM4E 4226/4885LMNA 567/4885ALDH1A1 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.