Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.55 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.55 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.55 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.55 |
| ▸ | KCNA3 known ✓ | P22001 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL206907 | 0.98 | LTA4H (0.66) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL2836396 | 0.98 | LTA4H (0.66) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL887619 | 0.98 | LTA4H (0.66) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL28734640 | 0.97 | LTA4H (0.64) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL30428 | 0.96 | LTA4H (0.68) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL28004820 | 0.95 | LTA4H (0.62) | LTA4HTP53TSHRFAAHPLA2G4B | |
| Phosphoric Acid SCHEMBL28816501 | 0.91 | LTA4H (0.69) | LTA4HTP53TSHRFAAHKCNA3 | |
| Phosphoric Acid SCHEMBL28248844 | 0.91 | LTA4H (0.57) | LTA4HTP53TSHRFAAHPLA2G4B | |
| SCHEMBL190814 | 0.89 | LTA4H (0.78) | LTA4HTP53TSHRFAAHPLA2G4B | |
| SCHEMBL192256 | 0.89 | LTA4H (0.78) | LTA4HTP53TSHRFAAHPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746820-B2 | CAPABLE OF FORMING AN IMAGE BY SCANNING EXPOSURE SUCH AS LASER; RESIST FOR FORMING A PRINTED WIRING BOARD, A COLOR FILTER OR A PHOSPHOR PATTERN | MITSUBISHI PAPER MILLS LIMITED (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20020182537-A1 | Light-sensitive composition and light-sensitive lithographic printing plate | MITSUBISHI PAPER MILLS LIMITED (JP) | 2002-12-05 | — | — | US | disclosed |