Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6834929

C1CCC2=NCCCN2CC1.N

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.95
USP2 O75604 2/20 0.95
ACHE P22303 6/20 0.37
NOS3 P29474 3/20 0.34
NOS1 P29475 3/20 0.34
NOS2 P35228 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6853620 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL2401189 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL17417853 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL3047 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL16583523 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL10601682 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
SCHEMBL2734323 0.98 INMT (1.00) INMTUSP2ACHENOS3NOS1
Iodide SCHEMBL23365018 0.95 INMT (0.95) INMTUSP2ACHENOS3NOS1
Fluoride SCHEMBL14777947 0.95 INMT (0.95) INMTUSP2ACHENOS3NOS1
SCHEMBL2544511 0.95 INMT (0.95) INMTUSP2ACHENOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756496-B1 SUCH AS TRIETHYLAMMONIUM-5'-DIMETHOXYTRITYL-3'-THYMIDINE-HYDROGEN PHOSPHONONDITHIOATE FOR USE AS ANTIVIRAL AND ANTICANCER AGENTS ISIS PHARMACEUTICALS, INC. 2004-06-29 US claimed
US-5194599-A Forming linkages with nuclosides and nucleotides; viricides, anticarcinogenic agents GILEAD SCIENCES, INC. (US) 1993-03-16 US claimed
EP-0360609-A2 Novel hydrogen phosphonodithioate compositions GILEAD SCIENCES, INC. (US) 1990-03-28 EP claimed
EP-3894475-B1 ASSEMBLY COMPONENTS COMPRISING CURABLE COMPOSITIONS CONTAINING ACETOACETYLATED RESINS EASTMAN CHEM CO (US) 2024-06-19 EP disclosed
EP-3894474-B1 CURABLE COMPOSITIONS COMPRISING ACETOACETYLATED RESINS, ALDEHYDES AND CERTAIN AMINES EASTMAN CHEM CO (US) 2023-09-13 EP disclosed
US-20230145775-A1 IMPACT RESISTANT GARMENT DESIGN BLUE LIMITED (GB) 2023-05-11 US disclosed
US-11530342-B2 Curable compositions comprising acetoacetylated resins, aldehydes and certain amines EASTMAN CHEMICAL COMPANY (US) 2022-12-20 US disclosed
US-11261359-B2 Flexible substrates comprising curable compositions containing acetoacetylated resins EASTMAN CHEMICAL COMPANY (US) 2022-03-01 US disclosed
US-20210403646-A1 ACID-CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2021-12-30 US disclosed
EP-3894476-A1 FLEXIBLE SUBSTRATES COMPRISING CURABLE COMPOSITIONS CONTAINING ACETOACETYLATED RESINS Eastman Chemical Company (US) 2021-10-20 EP disclosed
EP-3894474-A1 CURABLE COMPOSITIONS COMPRISING ACETOACETYLATED RESINS, ALDEHYDES AND CERTAIN AMINES Eastman Chemical Company (US) 2021-10-20 EP disclosed
US-5256775-A Having two or more phosphoramidiate linkages GILEAD SCIENCES, INC. (US) 1993-10-26 US disclosed
US-5194599-A Forming linkages with nuclosides and nucleotides; viricides, anticarcinogenic agents GILEAD SCIENCES, INC. (US) 1993-03-16 US disclosed
EP-0476071-A4 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME 1992-11-04 EP disclosed
EP-0476071-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1992-03-25 EP disclosed
WO-1992002535-A1 AUTOMATED SYSTEM FOR POLYNUCLEOTIDE SYNTHESIS AND PURIFICATION APPLIED BIOSYSTEMS, INC. (US) 1992-02-20 WO disclosed
US-5047524-A Solid phase syntheisis o nonsuelladle porous polystyrene support by phosphoramide or hydrogen phosphonate chemistry APPLIED BIOSYSTEMS, INC. (US) 1991-09-10 US disclosed
WO-1990015065-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1990-12-13 WO disclosed
EP-0375278-A2 Automated system for polynucleotide synthesis and purification THE PERKIN-ELMER CORPORATION (US) 1990-06-27 EP disclosed
EP-0360609-A2 Novel hydrogen phosphonodithioate compositions GILEAD SCIENCES, INC. (US) 1990-03-28 EP disclosed