Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447135 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL29373398 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL27615461 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL27634502 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10347205 | 0.85 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7749745 | 0.83 | MEN1 (0.61) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Acetic Acid SCHEMBL8010751 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL28117638 | 0.83 | ALDH1A1 (0.61) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL29609999 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL448000 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1352907-A1 | PROCESSES FOR PREPARING CALANOLIDE A AND INTERMEDIATES THEREOF | KURARAY CO., LTD. (JP) | 2003-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | CALR, CYP51A1, CYP4A11 | ALDH1A1 1043/4885HSD17B10 279/4885PGR 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.