Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | FABP7 | O15540 | 3/20 | 0.49 |
| ▸ | FABP3 | P05413 | 3/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347207 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL28117638 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11370297 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL5966176 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11716506 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL6835002 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL25244833 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL448000 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL5145481 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL5842272 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HSD17B10GAAPGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709309-B | Process for producing fluorine-containing cyclopropanecarboxylic acid | 中央硝子株式会社 | 2020-10-09 | — | — | CN | disclosed |
| US-10793540-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2020-10-06 | — | — | US | disclosed |
| US-10450291-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20180186763-A1 | Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2018-07-05 | — | — | US | disclosed |
| EP-3315497-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING CYCLOPROPANE CARBOXYLIC ACID COMPOUND | Central Glass Co., Ltd. (JP) | 2018-05-02 | — | — | EP | disclosed |
| CN-107709309-A | The manufacture method of fluorine-containing cyclopropane carboxylic acid acids | 中央硝子株式会社 | 2018-02-16 | — | — | CN | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| EP-0206810-B1 | ACRYLATE COMPOUND AND COMPOSITION CONTAINING THE SAME | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-04-04 | — | — | EP | disclosed |
| US-4755620-A | Acrylate compound and composition containing the same | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1988-07-05 | — | — | US | disclosed |
| EP-0206810-A2 | Acrylate compound and composition containing the same | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, KLK1, SERPINC1 | ALDH1A1 573/4885HSD17B10 242/4885GAA 2835/4885 |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | ALDH1A1 581/4885HSD17B10 255/4885GAA 2847/4885 |
| US-10793540-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | PFAS, FDPS, CYP2F1 | ALDH1A1 996/4885HSD17B10 494/4885GAA 1648/4885 |
| US-20180186763-A1 | Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound | PFAS, FDPS, FIBP | ALDH1A1 1093/4885HSD17B10 717/4885GAA 1594/4885 |
| US-10450291-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | PFAS, FDPS, FIBP | ALDH1A1 1093/4885HSD17B10 717/4885GAA 1594/4885 |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | ALDH1A1 581/4885HSD17B10 255/4885GAA 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.