Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.35 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834950 | 1.00 | P2RX3 (0.37) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL6834949 | 0.88 | P2RX3 (0.36) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL6831423 | 0.88 | P2RX3 (0.36) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL6833762 | 0.87 | ST6GAL1 (0.35) | — | |
| SCHEMBL6835037 | 0.87 | ST6GAL1 (0.35) | — | |
| SCHEMBL6834851 | 0.86 | P2RX3 (0.38) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL6836526 | 0.85 | TYMP (0.36) | TYMP | |
| SCHEMBL6835151 | 0.85 | TYMP (0.36) | TYMP | |
| SCHEMBL6835045 | 0.80 | ADORA1 (0.45) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL7266107 | 0.80 | ADORA1 (0.47) | ENPP1DOT1LTRDMT1CARM1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082774-A1 | Novel phosphate and thiophosphate protecting groups | ISIS PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082774-A1 | Novel phosphate and thiophosphate protecting groups | TYMP, MTAP, PPIP5K2 | P2RX3 447/4885P2RX4 633/4885P2RX2 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.