Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11384466 | 0.99 | CYP1A2 (0.53) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| SCHEMBL684263 | 0.96 | RECQL (0.53) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11381105 | 0.95 | RECQL (0.52) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| SCHEMBL682753 | 0.95 | CYP1A2 (0.58) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11381800 | 0.94 | CYP1A2 (0.56) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| SCHEMBL683540 | 0.92 | TSHR (0.50) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| SCHEMBL11384056 | 0.91 | RECQL (0.56) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| SCHEMBL682741 | 0.91 | CYP1A2 (0.52) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11381065 | 0.91 | TSHR (0.49) | CYP1A2CYP2C19RECQLTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11389670 | 0.90 | RECQL (0.55) | CYP1A2CYP2C19RECQLTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299832-A | Substituted theophylline compounds | FISONS LIMITED (GB) | 1981-11-10 | — | — | US | claimed |
| EP-0011399-A1 | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1980-05-28 | — | — | EP | claimed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | CYP1A2 4049/4885CYP2C19 4575/4885RECQL 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.