Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylcysteine SCHEMBL1384791 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3923959 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5291 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4437351 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL149212 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4437350 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3923962 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3688241 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5292 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4433756 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743429-B2 | Use of calcitonin gene-related peptide in the prevention and alleviation of asthma and related bronchospastic pulmonary diseases | SHERBROOKE UNIVERSITY (CA) | 2004-06-01 | — | — | US | claimed |
| US-6743429-B2 | Use of calcitonin gene-related peptide in the prevention and alleviation of asthma and related bronchospastic pulmonary diseases | SHERBROOKE UNIVERSITY (CA) | 2004-06-01 | — | — | US | disclosed |
| US-20020037846-A1 | USE OF CALCITONIN GENE-RELATED PEPTIDE IN THE PREVENTION AND ALLEVIATION OF ASTHMA AND RELATED BRONCHOSPASTIC PULMONARY DISEASES | UNIVERSITE DE SHERBROOKE (CA) | 2002-03-28 | — | — | US | disclosed |
| WO-1998003534-A1 | CALCITONIN GENE-RELATED PEPTIDE RECEPTOR COMPONENT FACTOR (HOUDC44) | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |
| EP-0821061-A2 | Calcitonin gene-related peptide receptor component factor (houdc44) | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5710024-A | Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44) | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |