SCHEMBL6835643

SCHEMBL6835643

COC(=O)c1cc2cc(OC)ccc2oc1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.76
ALDH1A1 P00352 6/20 0.76
HPGD P15428 3/20 0.76
CA12 O43570 2/20 0.76
CA2 P00918 2/20 0.76
CA3 P07451 2/20 0.76
CA6 P23280 2/20 0.76
CA5A P35218 2/20 0.76
CA7 P43166 2/20 0.76
CA9 Q16790 2/20 0.76
CA14 Q9ULX7 2/20 0.76
CA5B Q9Y2D0 2/20 0.76
CA1 P00915 1/20 0.76
MAOB P27338 6/20 0.76
GAA P10253 2/20 0.75
MAPT P10636 3/20 0.70
CYP2C9 P11712 1/20 0.70
CYP2C19 P33261 1/20 0.70
KMT2A Q03164 2/20 0.65
GLA P06280 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687148 0.88 MAOB (0.76) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL2032914 0.88 KDM4E (0.81) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL29963204 0.87 KDM4E (1.00) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL7527810 0.87 ALDH1A1 (1.00) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL978456 0.87 KDM4E (1.00) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL2031783 0.86 MAOB (1.00) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL17903543 0.86 MAOB (0.63) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL12838815 0.86 KDM4E (1.00) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL18589240 0.84 MAOB (0.70) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL29985431 0.84 KDM4E (0.68) KDM4EALDH1A1HPGDCA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-20040198859-A1 Photopolymerization systems and their use NGUYEN CHAU K (US) 2004-10-07 US disclosed
EP-0730201-B1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2001-05-09 EP disclosed