SCHEMBL6687148

SCHEMBL6687148

COC(=O)c1cc2ccc(OC)cc2oc1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.76
ALDH1A1 P00352 6/20 0.76
HPGD P15428 5/20 0.76
GAA P10253 3/20 0.76
SLC16A3 O15427 1/20 0.76
KDM4E B2RXH2 5/20 0.76
GLA P06280 2/20 0.76
CA12 O43570 1/20 0.76
CA2 P00918 1/20 0.76
CA3 P07451 1/20 0.76
CA4 P22748 1/20 0.76
CA6 P23280 1/20 0.76
CA7 P43166 1/20 0.76
CA9 Q16790 1/20 0.76
CA14 Q9ULX7 1/20 0.76
HSD17B10 Q99714 2/20 0.75
MAOA P21397 8/20 0.69
RAB9A P51151 2/20 0.67
NPC1 O15118 2/20 0.67
POLB P06746 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835643 0.88 KDM4E (0.76) MAOBALDH1A1HPGDGAAKDM4E
SCHEMBL52650 0.88 ALDH1A1 (0.81) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL1366230 0.88 ALDH1A1 (0.81) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL1366531 0.87 CYP2C19 (0.78) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL1104931 0.87 ALDH1A1 (1.00) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL203997 0.87 SLC16A3 (1.00) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL24176813 0.86 MAOB (0.76) MAOBALDH1A1HPGDGAAKDM4E
SCHEMBL1406462 0.86 MAOB (1.00) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL20414716 0.86 ALDH1A1 (0.69) MAOBALDH1A1HPGDGAASLC16A3
SCHEMBL19338224 0.86 ALDH1A1 (1.00) MAOBALDH1A1HPGDGAASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-20230229084-A1 CHEMICALLY AMPLIFIED PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE DRY FILM, PRODUCTION METHOD OF SUBSTRATE HAVING TEMPLATE FOR PLATING, AND PRODUCTION METHOD OF PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2023-07-20 US disclosed
US-20230229084-A1 CHEMICALLY AMPLIFIED PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE DRY FILM, PRODUCTION METHOD OF SUBSTRATE HAVING TEMPLATE FOR PLATING, AND PRODUCTION METHOD OF PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2023-07-20 US disclosed
WO-2022004290-A1 CHEMICALLY AMPLIFIED PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD FOR MANUFACTURING PLATING MOLD-ATTACHED SUBSTRATE, AND METHOD FOR MANUFACTURING PLATED OBJECT 東京応化工業株式会社 2022-01-06 WO disclosed
WO-2017011686-A1 FLUORESCENT PRODRUGS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2017-01-19 WO disclosed
US-20160115146-A1 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES CISTIM (BE) 2016-04-28 US disclosed
US-20160115146-A1 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES CISTIM (BE) 2016-04-28 US disclosed
WO-2004089995-A2 PHOTOPOLYMERIZATION SYSTEMS AND THEIR USE ALBEMARLE CORPORATION (US) 2004-10-21 WO disclosed
US-20040198859-A1 Photopolymerization systems and their use NGUYEN CHAU K (US) 2004-10-07 US disclosed
EP-0795790-B1 Peel-developable lithographic printing plate KODAK POLYCHROME GRAPHICS LLC (US) 2002-09-25 EP disclosed
EP-0730201-B1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2001-05-09 EP disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160115146-A1 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES SLC16A3, SLC16A1, SLC16A8 MAOB 3418/4885ALDH1A1 160/4885HPGD 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.