Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822811 | 0.96 | ALDH1A1 (0.38) | ALDH1A1HTR2CTSHRSLC6A4EPHX2 | |
| SCHEMBL6826198 | 0.82 | MAOB (0.37) | ALDH1A1KDM4E | |
| SCHEMBL6822755 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRSLC6A4KDM1ABCHE | |
| SCHEMBL6835727 | 0.78 | PTPRZ1 (0.40) | ALDH1A1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL6825928 | 0.77 | MAOB (0.40) | ALDH1A1KDM4E | |
| SCHEMBL4657643 | 0.76 | MAPT (0.37) | ALDH1A1HTR2CPOLBTSHRSLC6A4 | |
| SCHEMBL4656494 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRSLC6A4EPHX2KDM1A | |
| SCHEMBL6839309 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRSLC6A4EPHX2SLC6A3 | |
| SCHEMBL6841637 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRSLC6A4EPHX2KDM1A | |
| SCHEMBL6821404 | 0.74 | TSHR (0.40) | ALDH1A1TSHRSLC6A4SLC6A3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040143007-A1 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143007-A1 | Malononitrile compounds and their use as pesticides | MAL2, ME1, CBR3 | ALDH1A1 1262/4885HTR2C 3801/4885KDM4E 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.