Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.65 |
| ▸ | THRB | P10828 | 9/20 | 0.65 |
| ▸ | RARB | P10826 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RARA | P10276 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327143 | 1.00 | THRA (0.65) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL351935 | 1.00 | THRA (0.65) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL13617729 | 1.00 | THRA (0.65) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL75644 | 1.00 | THRA (0.65) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL4931942 | 1.00 | THRA (0.65) | THRATHRBRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11612075 | 0.98 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30595523 | 0.98 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11664844 | 0.98 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2677626 | 0.98 | RARB (0.64) | THRATHRBRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11612937 | 0.96 | RARB (0.62) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440962-A | High yield purification method of target protein | SK生物科学株式会社 | 2024-01-23 | — | — | CN | disclosed |
| CN-114258310-A | Bioprosthetic tissue preparation | 爱德华兹生命科学公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20190269784-A1 | Selective Inhibitors of the Polo-Like Kinase 1 Polo-Box Domain | UNIVERSITY OF SOUTH CAROLINA | 2019-09-05 | — | — | US | disclosed |
| US-20040018458-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5223384-A | Multilayer; paper support, subbing and photosensitive layer | KONICA CORPORATION (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0256820-B1 | THERMAL DEVELOPING LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5032499-A | High density, stability | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0256820-A2 | Thermal developing light-sensitive material | KONICA CORPORATION (JP) | 1988-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269784-A1 | Selective Inhibitors of the Polo-Like Kinase 1 Polo-Box Domain | PLK1, PLK4, PLK2 | THRA 4018/4885THRB 3382/4885RARB 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.