SCHEMBL6835910

SCHEMBL6835910

O=C(Oc1ccc(C2CCCCC2)cc1)C1CCCCC1.O=C(Oc1ccc(C2CCCCC2)cc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.67
POLB P06746 2/20 0.67
KMT2A Q03164 8/20 0.54
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 2/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
ALDH1A1 P00352 5/20 0.47
MAPT P10636 4/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
PARP10 Q53GL7 1/20 0.46
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
HAO1 Q9UJM8 1/20 0.44
PKM P14618 1/20 0.43
KMO O15229 1/20 0.43
SLC18A3 Q16572 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3737608 0.92 KMT2A (0.56) ELANEPOLBKMT2ASMN1; SMN2TDP1
SCHEMBL23487602 0.92 ELANE (0.78) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL5185070 0.87 KMT2A (0.70) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL1790370 0.86 ALDH1A1 (0.51) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL23487601 0.82 POLB (0.65) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL21864300 0.82 ELANE (0.64) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL8999821 0.81 RAB9A (0.60) ELANEPOLBKMT2ASMN1; SMN2TDP1
SCHEMBL10483690 0.80 ELANE (1.00) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL13198380 0.80 KMT2A (0.59) ELANEPOLBKMT2AHTTSMN1; SMN2
SCHEMBL10949493 0.80 POLB (0.76) ELANEPOLBKMT2AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682661-B2 BETWEEN 2 ELECTRODE LAYERS, CONTAINS A POLYMER DISPERSED LIQUID CRYSTAL FILM, CONSISTS OF A LIQUID CRYSTAL MIXTURE FORMING MICRODROPLETS IN AN OPTICALLY ISOTROPIC, TRANSPARENT POLYMER MATRIX, EXHIBITS ELECTRICALLY SWITCHABLE TRANSPARENCY MERCK PATENT GESELLSCHAFT (DE) 2004-01-27 US disclosed
US-6565769-B2 Low temperature, high speed switches MERCK PATENT GMBH (DE) 2003-05-20 US disclosed
EP-0591508-B2 ELECTROOPTICAL LIQUID CRYSTAL SYSTEM MERCK PATENT GMBH (DE) 2003-01-15 EP disclosed
US-20020158227-A1 Electrooptical liquid crystal system MERCK PATENT GMBH (DE) 2002-10-31 US disclosed
US-6187222-B1 POLYMER DISPERSED LIQUID CRYSTAL FILMS MERCK PATENT GMBH (DE) 2001-02-13 US disclosed
US-6042745-A Electrooptical liquid crystal system MERCK PATENT GMBH (DE) 2000-03-28 US disclosed
EP-0591508-B1 ELECTROOPTICAL LIQUID CRYSTAL SYSTEM MERCK PATENT GMBH (DE) 1999-07-07 EP disclosed
US-5746938-A Electrooptical liquid crystal system MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-05-05 US disclosed
US-5323251-A Liquid crystals dispersed in isotropic, transparent polymer matrix having Swiss cheese morphology; irradiation polymerization, curing MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-21 US disclosed
EP-0564869-A1 Electrooptical liquid crystal systems MERCK PATENT GmbH (DE) 1993-10-13 EP disclosed