Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679077 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 | |
| SCHEMBL679076 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 | |
| SCHEMBL679573 | 0.84 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 | |
| SCHEMBL2987621 | 0.84 | CCR6 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 | |
| SCHEMBL12815113 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 | |
| SCHEMBL679165 | 0.81 | PRKCA (0.40) | — | |
| SCHEMBL679166 | 0.81 | PRKCA (0.40) | — | |
| SCHEMBL678545 | 0.81 | PRKCA (0.40) | — | |
| SCHEMBL7094238 | 0.81 | PRKCA (0.40) | — | |
| SCHEMBL679115 | 0.80 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2L3MBTL1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |